Chapter 1 Introduction
1．1 Brief history of clinical epidemiology
1．2 Definition of clinical epidemiology
1．3 Roles of clinical epidemiology
1．4 Methodology of clinical epidemiologic study
1．5 Characteristics of clinical epidemiology

Chapter 2 Distribution of Disease
2．1 Measures of disease frequency
2．2 Epidemic disease occurrence
2．3 Distribution of disease by time，place and person

Chapter 3 Descriptive Study
3．1 Introduction
3．2 Case and case series report
3．3 Cross-sectional study
3．4 Ecological study

Chapter 4 Cohort Study
4．1 Introduction
4．2 Design of a cohort study
4．3 Data collection and analysis
4．4 Common bias and controlling
4．5 Advantages and disadvantages of cohort studies
4．6 Example of a cohort study

Chapter 5 Case-Control Studies
5．1 Overview of case-control studies
5．2 Design of case-control studies
5．3 Data collection and analysis
5．4 Common bias and controlling
5．5 Advantage and disadvantage of the case-control study

Chapter 6 Experimental Epidemiology
6．1 Basic ideas of experimental study
6．2 Clinical trial
6．3 Field trial
……
Chapter 7 Screening and Diagnostic Tests
Chapter 8 Bias and Interaction
Chapter 9 Cause of Disease and Causal Inference
Chapter 10 Disease prevention and surveillance
Chapter 11 Communicable Diseases Epidemiology
Chapter 12 Epidemiology of Non-communicable Disease
Chapter 13 Epidemiology of Public Health Emergencies
Chapter 14 Molecular Epidemiology
Chapter 15 Pharmacoepidemiology
Chapter 16 Evidence-based Medicine and Systematic Review
Chapter 17 Disease Prognosis
Chapter 18 Nosocomial Infections
Chapter 19 Epidemiology Design in Clinical Research
References